Antiretroviral drug regimens to prevent mother-to-child transmission of HIV: a review of scientific, program, and policy advances for sub-Saharan Africa.
Identifieur interne : 002B02 ( Main/Exploration ); précédent : 002B01; suivant : 002B03Antiretroviral drug regimens to prevent mother-to-child transmission of HIV: a review of scientific, program, and policy advances for sub-Saharan Africa.
Auteurs : Benjamin H. Chi [Zambie] ; Jeffrey S A. Stringer ; Dhayendre MoodleySource :
- Current HIV/AIDS reports [ 1548-3576 ] ; 2013.
Descripteurs français
- KwdFr :
- Adulte, Afrique subsaharienne (épidémiologie), Agents antiVIH, Allaitement maternel, Centres de protection maternelle et infantile (organisation et administration), Complications de la grossesse et maladies infectieuses (), Complications de la grossesse et maladies infectieuses (épidémiologie), Enfant, Enfant d'âge préscolaire, Femelle, Grossesse, Humains, Infections à VIH (), Infections à VIH (transmission), Mâle, Mères, Nourrisson, Nouveau-né, Politique de santé, Processus politique, Transmission verticale de maladie infectieuse (), Évaluation de programme.
- MESH :
- organisation et administration : Centres de protection maternelle et infantile.
- épidémiologie : Afrique subsaharienne, Complications de la grossesse et maladies infectieuses, Infections à VIH.
- Adulte, Agents antiVIH, Allaitement maternel, Complications de la grossesse et maladies infectieuses, Enfant, Enfant d'âge préscolaire, Femelle, Grossesse, Humains, Infections à VIH, Mâle, Mères, Nourrisson, Nouveau-né, Politique de santé, Processus politique, Transmission verticale de maladie infectieuse, Évaluation de programme.
English descriptors
- KwdEn :
- Adult, Africa South of the Sahara (epidemiology), Anti-HIV Agents, Breast Feeding, Child, Child, Preschool, Female, HIV Infections (prevention & control), HIV Infections (transmission), Health Policy, Humans, Infant, Infant, Newborn, Infectious Disease Transmission, Vertical (prevention & control), Infectious Disease Transmission, Vertical (statistics & numerical data), Male, Maternal-Child Health Centers (organization & administration), Mothers, Policy Making, Pregnancy, Pregnancy Complications, Infectious (epidemiology), Pregnancy Complications, Infectious (prevention & control), Program Evaluation.
- MESH :
- chemical : Anti-HIV Agents.
- geographic , epidemiology : Africa South of the Sahara.
- epidemiology : Pregnancy Complications, Infectious.
- organization & administration : Maternal-Child Health Centers.
- prevention & control : HIV Infections, Infectious Disease Transmission, Vertical, Pregnancy Complications, Infectious.
- statistics & numerical data : Infectious Disease Transmission, Vertical.
- transmission : HIV Infections.
- Adult, Breast Feeding, Child, Child, Preschool, Female, Health Policy, Humans, Infant, Infant, Newborn, Male, Mothers, Policy Making, Pregnancy, Program Evaluation.
Abstract
Considerable advances have been made in the effort to prevent mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Clinical trials have demonstrated the efficacy of antiretroviral regimens to interrupt HIV transmission through the antenatal, intrapartum, and postnatal periods. Scientific discoveries have been rapidly translated into health policy, bolstered by substantial investment in health infrastructure capable of delivering increasingly complex services. A new scientific agenda is also emerging, one that is focused on the challenges of effective and sustainable program implementation. Finally, global campaigns to "virtually eliminate" pediatric HIV and dramatically reduce HIV-related maternal mortality have mobilized new resources and renewed political will. Each of these developments marks a major step in regional PMTCT efforts; their convergence signals a time of rapid progress in the field, characterized by an increased interdependency between clinical research, program implementation, and policy. In this review, we take stock of recent advances across each of these areas, highlighting the challenges--and opportunities--of improving health services for HIV-infected mothers and their children across the region.
DOI: 10.1007/s11904-013-0154-z
PubMed: 23440538
Affiliations:
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Chi</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Infectious Disease Research in Zambia, Lusaka, Zambia. bchi@cidrz.org</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Centre for Infectious Disease Research in Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Stringer, Jeffrey S A" sort="Stringer, Jeffrey S A" uniqKey="Stringer J" first="Jeffrey S A" last="Stringer">Jeffrey S A. Stringer</name></author><author><name sortKey="Moodley, Dhayendre" sort="Moodley, Dhayendre" uniqKey="Moodley D" first="Dhayendre" last="Moodley">Dhayendre Moodley</name></author></analytic><series><title level="j">Current HIV/AIDS reports</title><idno type="eISSN">1548-3576</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Africa South of the Sahara (epidemiology)</term><term>Anti-HIV Agents</term><term>Breast Feeding</term><term>Child</term><term>Child, Preschool</term><term>Female</term><term>HIV Infections (prevention & control)</term><term>HIV Infections (transmission)</term><term>Health Policy</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Infectious Disease Transmission, Vertical (prevention & control)</term><term>Infectious Disease Transmission, Vertical (statistics & numerical data)</term><term>Male</term><term>Maternal-Child Health Centers (organization & administration)</term><term>Mothers</term><term>Policy Making</term><term>Pregnancy</term><term>Pregnancy Complications, Infectious (epidemiology)</term><term>Pregnancy Complications, Infectious (prevention & control)</term><term>Program Evaluation</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Afrique subsaharienne (épidémiologie)</term><term>Agents antiVIH</term><term>Allaitement maternel</term><term>Centres de protection maternelle et infantile (organisation et administration)</term><term>Complications de la grossesse et maladies infectieuses ()</term><term>Complications de la grossesse et maladies infectieuses (épidémiologie)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Grossesse</term><term>Humains</term><term>Infections à VIH ()</term><term>Infections à VIH (transmission)</term><term>Mâle</term><term>Mères</term><term>Nourrisson</term><term>Nouveau-né</term><term>Politique de santé</term><term>Processus politique</term><term>Transmission verticale de maladie infectieuse ()</term><term>Évaluation de programme</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Africa South of the Sahara</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Pregnancy Complications, Infectious</term></keywords><keywords scheme="MESH" qualifier="organisation et administration" xml:lang="fr"><term>Centres de protection maternelle et infantile</term></keywords><keywords scheme="MESH" qualifier="organization & administration" xml:lang="en"><term>Maternal-Child Health Centers</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>HIV Infections</term><term>Infectious Disease Transmission, Vertical</term><term>Pregnancy Complications, Infectious</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Infectious Disease Transmission, Vertical</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Afrique subsaharienne</term><term>Complications de la grossesse et maladies infectieuses</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Breast Feeding</term><term>Child</term><term>Child, Preschool</term><term>Female</term><term>Health Policy</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Mothers</term><term>Policy Making</term><term>Pregnancy</term><term>Program Evaluation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Agents antiVIH</term><term>Allaitement maternel</term><term>Complications de la grossesse et maladies infectieuses</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Grossesse</term><term>Humains</term><term>Infections à VIH</term><term>Mâle</term><term>Mères</term><term>Nourrisson</term><term>Nouveau-né</term><term>Politique de santé</term><term>Processus politique</term><term>Transmission verticale de maladie infectieuse</term><term>Évaluation de programme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Considerable advances have been made in the effort to prevent mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. 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In this review, we take stock of recent advances across each of these areas, highlighting the challenges--and opportunities--of improving health services for HIV-infected mothers and their children across the region.</div></front></TEI><affiliations><list><country><li>Zambie</li></country></list><tree><noCountry><name sortKey="Moodley, Dhayendre" sort="Moodley, Dhayendre" uniqKey="Moodley D" first="Dhayendre" last="Moodley">Dhayendre Moodley</name><name sortKey="Stringer, Jeffrey S A" sort="Stringer, Jeffrey S A" uniqKey="Stringer J" first="Jeffrey S A" last="Stringer">Jeffrey S A. Stringer</name></noCountry><country name="Zambie"><noRegion><name sortKey="Chi, Benjamin H" sort="Chi, Benjamin H" uniqKey="Chi B" first="Benjamin H" last="Chi">Benjamin H. Chi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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